Cellular Nrf2 Levels Determine Cell Fate during Chemical Carcinogenesis in Esophageal Epithelium

Nrf2 is essential for cytoprotection against carcinogens, and through systemic Nrf2 knockout mice, Nrf2-deficient cells were shown to be susceptible to chemical carcinogens and prone to developing cancers. However, the oncogenic potential of Nrf2-deficient epithelial cells surrounded by normal cells...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Horiuchi, Makoto, Taguchi, Keiko, Hirose, Wataru, Tsuchida, Kouhei, Suzuki, Mikiko, Taniyama, Yusuke, Kamei, Takashi, Yamamoto, Masayuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093497/
https://ncbi.nlm.nih.gov/pubmed/33257504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00536-20
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