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Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers
Keap1-Nrf2 system plays a central role in the stress response. While Keap1 ubiquitinates Nrf2 for degradation under unstressed conditions, this Keap1 activity is abrogated in response to oxidative or electrophilic stresses, leading to Nrf2 stabilization and coordinated activation of cytoprotective g...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023823/ https://ncbi.nlm.nih.gov/pubmed/24379438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01384-13 |
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