Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H(2)O(2), forms a powerful antimicrobia...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rehring, Jacob F., Bui, Triet M., Galán-Enríquez, Carlos Samuel, Urbanczyk, Jessica M., Ren, Xingsheng, Wiesolek, Hannah L., Sullivan, David P., Sumagin, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093447/
https://ncbi.nlm.nih.gov/pubmed/33959129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.654259
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