Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H(2)O(2), forms a powerful antimicrobia...

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Pubblicato in:Front Immunol
Autori principali: Rehring, Jacob F., Bui, Triet M., Galán-Enríquez, Carlos Samuel, Urbanczyk, Jessica M., Ren, Xingsheng, Wiesolek, Hannah L., Sullivan, David P., Sumagin, Ronen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093447/
https://ncbi.nlm.nih.gov/pubmed/33959129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.654259
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