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miR-23a/b suppress cGAS-mediated innate and autoimmunity
Cyclic GMP-AMP synthase (cGAS), a key sensor of intracellular DNA, is essential for eliciting innate immunity against infection, whereas aberrant activation of cGAS by endogenous DNA promotes severe autoimmune diseases. However, it is largely unknown how cGAS expression is regulated during pathogen...
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| I publikationen: | Cell Mol Immunol |
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| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8093233/ https://ncbi.nlm.nih.gov/pubmed/33767433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-021-00668-x |
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