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Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps

Rishirilides are a group of PKS II secondary metabolites produced by Streptomyces bottropensis Gö C4/4. Biosynthetic studies in the past have elucidated early and late steps of rishirilide biosynthesis. This work is aiming to solve the remaining steps in the rishirilide biosynthesis. Inactivation of...

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Detalhes bibliográficos
Publicado no:Mol Biotechnol
Main Authors: Alali, Ahmad, Zhang, Lin, Li, Jianyu, Zuo, Chijian, Wassouf, Dimah, Yan, Xiaohui, Schwarzer, Philipp, Günther, Stefan, Einsle, Oliver, Bechthold, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093152/
https://ncbi.nlm.nih.gov/pubmed/33763824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-021-00314-x
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