Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity against SARS-CoV-2

Molnupiravir (EIDD-2801/MK-4482), the prodrug of the active antiviral ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931), has activity against a number of RNA viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), severe acute respiratory syndrome coronavirus (SA...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Painter, Wendy P., Holman, Wayne, Bush, Jim A., Almazedi, Firas, Malik, Hamzah, Eraut, Nicola C. J. E., Morin, Merribeth J., Szewczyk, Laura J., Painter, George R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092915/
https://ncbi.nlm.nih.gov/pubmed/33649113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02428-20
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