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Emergence of Two AcrB Substitutions Conferring Multidrug Resistance to Salmonella spp.

AcrAB-TolC is a major tripartite multidrug efflux pump conferring resistance to a wide variety of compounds in Gram-negative pathogens. Many AcrB mutants have been constructed through site-directed mutagenesis to probe the mechanism of AcrB function in antibiotic resistance. However, much less is kn...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Yang, Ling, Shi, Haiyang, Zhang, Lijuan, Lin, Xiaoling, Wei, Yinan, Jiang, Hongxia, Zeng, Zhenling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092907/
https://ncbi.nlm.nih.gov/pubmed/33685897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-20
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