Overexpression of the Multidrug Efflux Operon acrEF by Insertional Activation with IS1 or IS10 Elements in Salmonella enterica Serovar Typhimurium DT204 acrB Mutants Selected with Fluoroquinolones

High-level fluoroquinolone (FQ) resistance in Salmonella enterica serovar Typhimurium phage type DT204 has been previously shown to be essentially due to both multiple target gene mutations and active efflux by the AcrAB-TolC efflux system. In this study we show that in intermediatly resistant acrB-...

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Main Authors: Olliver, Anne, Vallé, Michel, Chaslus-Dancla, Elisabeth, Cloeckaert, Axel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC538886/
https://ncbi.nlm.nih.gov/pubmed/15616308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.289-301.2005
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