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Population Pharmacokinetics and Monte Carlo Simulation for Dosage Optimization of Fosfomycin in the Treatment of Osteoarticular Infections in Patients without Renal Dysfunction

Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to multidrug-resistant (MDR) pathogens. Our aims were to conduct population pharmacokinetics of fosfomycin in a cohort of OI patients receiving 16 g daily by intermittent (II) or continuous (CI) infusion an...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Rinaldi, Matteo, Cojutti, Pier Giorgio, Zamparini, Eleonora, Tedeschi, Sara, Rossi, Nicolò, Conti, Matteo, Giannella, Maddalena, Pea, Federico, Viale, Pierluigi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092888/
https://ncbi.nlm.nih.gov/pubmed/33619055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02038-20
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