Population Pharmacokinetics and Monte Carlo Simulation for Dosage Optimization of Fosfomycin in the Treatment of Osteoarticular Infections in Patients without Renal Dysfunction

Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to multidrug-resistant (MDR) pathogens. Our aims were to conduct population pharmacokinetics of fosfomycin in a cohort of OI patients receiving 16 g daily by intermittent (II) or continuous (CI) infusion an...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Rinaldi, Matteo, Cojutti, Pier Giorgio, Zamparini, Eleonora, Tedeschi, Sara, Rossi, Nicolò, Conti, Matteo, Giannella, Maddalena, Pea, Federico, Viale, Pierluigi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Clinical Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092888/
https://ncbi.nlm.nih.gov/pubmed/33619055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02038-20
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