Population Pharmacokinetics and Monte Carlo Simulation for Dosage Optimization of Fosfomycin in the Treatment of Osteoarticular Infections in Patients without Renal Dysfunction

Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to multidrug-resistant (MDR) pathogens. Our aims were to conduct population pharmacokinetics of fosfomycin in a cohort of OI patients receiving 16 g daily by intermittent (II) or continuous (CI) infusion an...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rinaldi, Matteo, Cojutti, Pier Giorgio, Zamparini, Eleonora, Tedeschi, Sara, Rossi, Nicolò, Conti, Matteo, Giannella, Maddalena, Pea, Federico, Viale, Pierluigi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092888/
https://ncbi.nlm.nih.gov/pubmed/33619055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02038-20
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