Population Pharmacokinetics and Monte Carlo Simulation for Dosage Optimization of Fosfomycin in the Treatment of Osteoarticular Infections in Patients without Renal Dysfunction

Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to multidrug-resistant (MDR) pathogens. Our aims were to conduct population pharmacokinetics of fosfomycin in a cohort of OI patients receiving 16 g daily by intermittent (II) or continuous (CI) infusion an...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Rinaldi, Matteo, Cojutti, Pier Giorgio, Zamparini, Eleonora, Tedeschi, Sara, Rossi, Nicolò, Conti, Matteo, Giannella, Maddalena, Pea, Federico, Viale, Pierluigi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092888/
https://ncbi.nlm.nih.gov/pubmed/33619055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02038-20
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