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Insight into Vaccine Development for Alphacoronaviruses Based on Structural and Immunological Analyses of Spike Proteins

Coronaviruses that infect humans belong to the Alphacoronavirus (including HCoV-229E) and Betacoronavirus (including SARS-CoV and SARS-CoV-2) genera. In particular, SARS-CoV-2 is currently a major threat to public health worldwide. The spike (S) homotrimers bind to their receptors via the receptor-b...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Shi, Yuejun, Shi, Jiale, Sun, Limeng, Tan, Yubei, Wang, Gang, Guo, Fenglin, Hu, Guangli, Fu, Yanan, Fu, Zhen F., Xiao, Shaobo, Peng, Guiqing
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092709/
https://ncbi.nlm.nih.gov/pubmed/33414160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02284-20
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