Trypsin-Enhanced Infection with Porcine Epidemic Diarrhea Virus Is Determined by the S2 Subunit of the Spike Glycoprotein

Porcine epidemic diarrhea virus (PEDV) is an enteric pathogen of importance to the swine industry, causing high mortality in neonatal piglets. Efficient PEDV infection usually relies on the presence of trypsin, yet the mechanism of trypsin dependency is ambiguous. Here, we identified two PEDV strain...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Tan, Yubei, Sun, Limeng, Wang, Gang, Shi, Yuejun, Dong, Wanyu, Fu, Yanan, Fu, Zhen, Chen, Huanchun, Peng, Guiqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139691/
https://ncbi.nlm.nih.gov/pubmed/33692210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02453-20
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