Trypsin-Enhanced Infection with Porcine Epidemic Diarrhea Virus Is Determined by the S2 Subunit of the Spike Glycoprotein

Porcine epidemic diarrhea virus (PEDV) is an enteric pathogen of importance to the swine industry, causing high mortality in neonatal piglets. Efficient PEDV infection usually relies on the presence of trypsin, yet the mechanism of trypsin dependency is ambiguous. Here, we identified two PEDV strain...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Tan, Yubei, Sun, Limeng, Wang, Gang, Shi, Yuejun, Dong, Wanyu, Fu, Yanan, Fu, Zhen, Chen, Huanchun, Peng, Guiqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8139691/
https://ncbi.nlm.nih.gov/pubmed/33692210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02453-20
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