The Immunological Impact of Adenovirus Early Genes on Vaccine-Induced Responses in Mice and Nonhuman Primates

Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Ad with a deletion in early region 3 (ΔE3) provokes a stronger immune response than Ad with deletions in early regions 1 and E3 (ΔE1/ΔE3). The ΔE1/ΔE3 Ads are more popular becau...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Sangare, Kotou, Tuero, Iskra, Rahman, Mohammad Arif, Hoang, Tanya, Miller-Novak, Leia K., Vargas-Inchaustegui, Diego A., Venzon, David J., LaBranche, Celia, Montefiori, David C., Robert-Guroff, Marjorie, Thomas, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092689/
https://ncbi.nlm.nih.gov/pubmed/33441339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02253-20
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