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Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector
Type 5 human adenoviruses (Ad5) deleted of genes encoding the early region 1B 55-kDa (E1B55K) protein including Onyx-015 (dl1520) and H101 are best known for their oncolytic potential. As a vaccine vector the E1B55K deletion may allow for the insertion of a transgene nearly 1,000 base pairs larger t...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4938603/ https://ncbi.nlm.nih.gov/pubmed/27391605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158505 |
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