Cargando...

E4orf1 Limits the Oncolytic Potential of the E1B-55K Deletion Mutant Adenovirus

Clinical trials have shown oncolytic adenoviruses to be tumor selective with minimal toxicity toward normal tissue. The virus ONYX-015, in which the gene encoding the early region 1B 55-kDa (E1B-55K) protein is deleted, has been most effective when used in combination with either chemotherapy or rad...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Thomas, Michael A., Broughton, Robin S., Goodrum, Felicia D., Ornelles, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648266/
https://ncbi.nlm.nih.gov/pubmed/19129452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01972-08
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!