Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

Insulin and insulin-like growth factor 1 (IGF-1) receptors share many downstream signaling pathways but have unique biological effects. To define the molecular signals contributing to these distinct activities, we performed global phosphoproteomics on cells expressing either insulin receptor (IR), I...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Nagao, Hirofumi, Cai, Weikang, Wewer Albrechtsen, Nicolai J., Steger, Martin, Batista, Thiago M., Pan, Hui, Dreyfuss, Jonathan M., Mann, Matthias, Kahn, C. Ronald
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092608/
https://ncbi.nlm.nih.gov/pubmed/33879610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019474118
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