Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

Insulin and insulin-like growth factor 1 (IGF-1) receptors share many downstream signaling pathways but have unique biological effects. To define the molecular signals contributing to these distinct activities, we performed global phosphoproteomics on cells expressing either insulin receptor (IR), I...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Nagao, Hirofumi, Cai, Weikang, Wewer Albrechtsen, Nicolai J., Steger, Martin, Batista, Thiago M., Pan, Hui, Dreyfuss, Jonathan M., Mann, Matthias, Kahn, C. Ronald
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2021
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092608/
https://ncbi.nlm.nih.gov/pubmed/33879610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019474118
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