Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore

Glioblastoma (GBM) is the most common primary malignant tumor of the central nervous system with a dismal prognosis. Locoregional failure is common despite high doses of radiation therapy, which has prompted great interest in developing novel strategies to radiosensitize these cancers. Our group pre...

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Udgivet i:Oncotarget
Main Authors: Paradkar, Sateja, Herrington, James, Hendricson, Adam, Hewawasam, Piyasena, Plummer, Mark, Hoyer, Denton, Sundaram, Ranjini K., Surovtseva, Yulia V., Bindra, Ranjit S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092340/
https://ncbi.nlm.nih.gov/pubmed/33953843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27933
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