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Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

Herpes simplex virus 1 (HSV-1) requires seven proteins to package its genome through a vertex in its capsid, one of which is the portal protein, pUL6. The portal protein is also thought to facilitate assembly of the procapsid. While the portal has been visualized in mature capsids, we aimed to eluci...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Buch, Michael H. C., Newcomb, William W., Winkler, Dennis C., Steven, Alasdair C., Heymann, J. Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092310/
https://ncbi.nlm.nih.gov/pubmed/33727359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03575-20
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