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Cryo-electron tomography of bacteriophage ϕ6 procapsids shows random occupancy of the binding sites for RNA polymerase and packaging NTPase

Assembly of dsRNA bacteriophage ϕ6 involves packaging of the three mRNA strands of the segmented genome into the procapsid, an icosahedrally symmetric particle with recessed vertices. The hexameric packaging NTPase (P4) overlies these vertices, and the monomeric RNA-dependent RNA polymerase (RdRP, P...

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Detalhes bibliográficos
Main Authors: Nemecek, Daniel, Heymann, J. Bernard, Qiao, Jian, Mindich, Leonard, Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910799/
https://ncbi.nlm.nih.gov/pubmed/20538059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.06.005
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