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Structural Changes in Influenza Virus at Low pH Characterized by Cryo-Electron Tomography
Influenza virus enters host cells by endocytosis. The low pH of endosomes triggers conformational changes in hemagglutinin (HA) that mediate fusion of the viral and endosomal membranes. We have used cryo-electron tomography to visualize influenza A virus at pH 4.9, a condition known to induce fusoge...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302323/ https://ncbi.nlm.nih.gov/pubmed/22258245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06698-11 |
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