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Structural Changes in Influenza Virus at Low pH Characterized by Cryo-Electron Tomography
Influenza virus enters host cells by endocytosis. The low pH of endosomes triggers conformational changes in hemagglutinin (HA) that mediate fusion of the viral and endosomal membranes. We have used cryo-electron tomography to visualize influenza A virus at pH 4.9, a condition known to induce fusoge...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302323/ https://ncbi.nlm.nih.gov/pubmed/22258245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06698-11 |
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