Allelic Interference in Prion Replication Is Modulated by the Convertibility of the Interfering PrP(C) and Other Host-Specific Factors

Early studies in transgenic mouse lines have shown that the coexpression of endogenous murine prion protein (PrP(C)) and transgenic PrP(C) from another species either inhibits or allows the propagation of prions, depending on the infecting prion strain and interacting protein species. The way whereb...

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Udgivet i:mBio
Main Authors: Espinosa, Juan Carlos, Andreoletti, Olivier, Marín-Moreno, Alba, Lugan, Severine, Aguilar-Calvo, Patricia, Cassard, Hervé, Lorenzo, Patricia, Douet, Jean-Yves, Villa-Díaz, Ana, Aron, Naima, Prieto, Irene, Huor, Alvina, Torres, Juan María
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092304/
https://ncbi.nlm.nih.gov/pubmed/33727358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03508-20
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