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Inactivation of the Pta-AckA Pathway Impairs Fitness of Bacillus anthracis during Overflow Metabolism
Under conditions of glucose excess, aerobically growing bacteria predominantly direct carbon flux toward acetate fermentation, a phenomenon known as overflow metabolism or the bacterial “Crabtree effect.” Numerous studies of the major acetate-generating pathway, the phosphotransacetylase (Pta)-aceta...
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| Veröffentlicht in: | J Bacteriol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092162/ https://ncbi.nlm.nih.gov/pubmed/33593944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00660-20 |
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