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Inactivation of the Pta-AckA Pathway Impairs Fitness of Bacillus anthracis during Overflow Metabolism

Under conditions of glucose excess, aerobically growing bacteria predominantly direct carbon flux toward acetate fermentation, a phenomenon known as overflow metabolism or the bacterial “Crabtree effect.” Numerous studies of the major acetate-generating pathway, the phosphotransacetylase (Pta)-aceta...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Won, Harim I., Watson, Sean M., Ahn, Jong-Sam, Endres, Jennifer L., Bayles, Kenneth W., Sadykov, Marat R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092162/
https://ncbi.nlm.nih.gov/pubmed/33593944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00660-20
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