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Inactivation of the Pta-AckA Pathway Causes Cell Death in Staphylococcus aureus

During growth under conditions of glucose and oxygen excess, Staphylococcus aureus predominantly accumulates acetate in the culture medium, suggesting that the phosphotransacetylase-acetate kinase (Pta-AckA) pathway plays a crucial role in bacterial fitness. Previous studies demonstrated that these...

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Detalhes bibliográficos
Main Authors: Sadykov, Marat R., Thomas, Vinai C., Marshall, Darrell D., Wenstrom, Christopher J., Moormeier, Derek E., Widhelm, Todd J., Nuxoll, Austin S., Powers, Robert, Bayles, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697545/
https://ncbi.nlm.nih.gov/pubmed/23625849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00042-13
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