The hypoferremic response to acute inflammation is maintained in thalassemia mice even under parenteral iron loading

BACKGROUND: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. Hepcidin expression is influenced by multiple factors, including iron stores, ineffective erythropoiesis, and inflammation. However,...

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Publicado en:PeerJ
Autores principales: Sanyear, Chanita, Chiawtada, Buraporn, Butthep, Punnee, Svasti, Saovaros, Fucharoen, Suthat, Masaratana, Patarabutr
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092106/
https://ncbi.nlm.nih.gov/pubmed/33987030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11367
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