The hypoferremic response to acute inflammation is maintained in thalassemia mice even under parenteral iron loading

BACKGROUND: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. Hepcidin expression is influenced by multiple factors, including iron stores, ineffective erythropoiesis, and inflammation. However,...

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Bibliographische Detailangaben
Veröffentlicht in:PeerJ
Hauptverfasser: Sanyear, Chanita, Chiawtada, Buraporn, Butthep, Punnee, Svasti, Saovaros, Fucharoen, Suthat, Masaratana, Patarabutr
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2021
Schlagworte:
Biochemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092106/
https://ncbi.nlm.nih.gov/pubmed/33987030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11367
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