The hypoferremic response to acute inflammation is maintained in thalassemia mice even under parenteral iron loading

BACKGROUND: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. Hepcidin expression is influenced by multiple factors, including iron stores, ineffective erythropoiesis, and inflammation. However,...

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Vydáno v:PeerJ
Hlavní autoři: Sanyear, Chanita, Chiawtada, Buraporn, Butthep, Punnee, Svasti, Saovaros, Fucharoen, Suthat, Masaratana, Patarabutr
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2021
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092106/
https://ncbi.nlm.nih.gov/pubmed/33987030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11367
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