Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1(c259)T Cells in Synovial Sarcoma

We evaluated the safety and activity of autologous T cells expressing NY-ESO-1(c259), an affi nity-enhanced T-cell receptor (TCR) recognizing an HLA-A2–restricted NY-ESO-1/LAGE1a—derived peptide, in patients with metastatic synovial sarcoma (NY-ESO-1(c259)T cells). Confi rmed antitumor responses occ...

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Argitaratua izan da:Cancer Discov
Egile Nagusiak: D'Angelo, Sandra P., Melchiori, Luca, Merchant, Melinda S., Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D., Chagin, Karen, Binder, Gwendolyn K., Basu, Samik, Lowther, Daniel E., Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K., Winkle, Erin Van, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092079/
https://ncbi.nlm.nih.gov/pubmed/29891538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1417
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