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Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1(c259)T Cells in Synovial Sarcoma
We evaluated the safety and activity of autologous T cells expressing NY-ESO-1(c259), an affi nity-enhanced T-cell receptor (TCR) recognizing an HLA-A2–restricted NY-ESO-1/LAGE1a—derived peptide, in patients with metastatic synovial sarcoma (NY-ESO-1(c259)T cells). Confi rmed antitumor responses occ...
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| Udgivet i: | Cancer Discov |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092079/ https://ncbi.nlm.nih.gov/pubmed/29891538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1417 |
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