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BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome

Histone-modifying systems play fundamental roles in gene regulation and the development of multicellular organisms. Histone modifications that are enriched at gene regulatory elements have been heavily studied, but the function of modifications found more broadly throughout the genome remains poorly...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Fursova, Nadezda A., Turberfield, Anne H., Blackledge, Neil P., Findlater, Emma L., Lastuvkova, Anna, Huseyin, Miles K., Dobrinić, Paula, Klose, Robert J.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091973/
https://ncbi.nlm.nih.gov/pubmed/33888563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.347005.120
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