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Identification of non-covalent 3C-like protease inhibitors against severe acute respiratory syndrome coronavirus-2 via virtual screening of a Korean compound library
The outbreak of coronavirus (CoV) disease 2019 (COVID-19) caused by the severe acute respiratory syndrome CoV-2 (SARS-CoV-2) has turned into a pandemic. The enzyme 3C-like protease (3CL(pro)) is essential for the maturation of viral polyproteins in SARS-CoV-2 and is therefore regarded as a key drug...
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| Publicado en: | Bioorg Med Chem Lett |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Authors. Published by Elsevier Ltd.
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091729/ https://ncbi.nlm.nih.gov/pubmed/33957246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2021.128067 |
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