Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca(2+) mobilization and the inflammatory activity of dendritic cells

Innate immune responses to Gram-negative bacteria depend on the recognition of lipopolysaccharide (LPS) by a receptor complex that includes CD14 and TLR4. In dendritic cells (DCs), CD14 enhances the activation not only of TLR4 but also that of the NFAT family of transcription factors, which suppress...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Signal
Prif Awduron: Marongiu, Laura, Mingozzi, Francesca, Cigni, Clara, Marzi, Roberta, Di Gioia, Marco, Garrè, Massimiliano, Parazzoli, Dario, Sironi, Laura, Collini, Maddalena, Sakaguchi, Reiko, Morii, Takashi, Crosti, Mariacristina, Moro, Monica, Schurmans, Stéphane, Catelani, Tiziano, Rotem, Rany, Colombo, Miriam, Shears, Stephen, Prosperi, Davide, Zanoni, Ivan, Granucci, Francesca
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091591/
https://ncbi.nlm.nih.gov/pubmed/33785611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaz2120
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