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Germline IKZF1mutations and their impact on immunity: IKAROS-associated diseases and pathophysiology
INTRODUCTION: The transcription factor IKAROS and IKAROS family members are critical for the development of lymphocyte and other blood cell lineages. Germline heterozygous IKZF1 mutations have been described in primary immunodeficiency as well as in human hematologic malignancies, affecting both B a...
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| Udgivet i: | Expert Rev Clin Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091572/ https://ncbi.nlm.nih.gov/pubmed/33691560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1744666X.2021.1901582 |
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