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IKAROS-associated diseases in primary immunodeficiency patients
Ikaros zinc finger 1 (IKZF1 or Ikaros) is a hematopoietic zinc finger DNA-binding transcription factor that acts as a critical regulator of lymphocyte and myeloid differentiation. Somatic mutations in IKAROS are frequent and a sign of poor prognosis in B-cell progenitor acute lymphoblastic leukemia...
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| Publié dans: | Immunol Allergy Clin North Am |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7394939/ https://ncbi.nlm.nih.gov/pubmed/32654692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.iac.2020.04.004 |
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