IKAROS-associated diseases in primary immunodeficiency patients

Ikaros zinc finger 1 (IKZF1 or Ikaros) is a hematopoietic zinc finger DNA-binding transcription factor that acts as a critical regulator of lymphocyte and myeloid differentiation. Somatic mutations in IKAROS are frequent and a sign of poor prognosis in B-cell progenitor acute lymphoblastic leukemia...

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Bibliographic Details
Published in:	Immunol Allergy Clin North Am
Main Authors:	Nunes-Santos, Cristiane J, Kuehn, Hye Sun, Rosenzweig, Sergio D.
Format:	Artigo
Language:	Inglês
Published:	2020
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7394939/ https://ncbi.nlm.nih.gov/pubmed/32654692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.iac.2020.04.004
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IKAROS-associated diseases in primary immunodeficiency patients

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