BFAR coordinates TGFβ signaling to modulate Th9-mediated cancer immunotherapy

TGFβ is essential for the generation of anti-tumor Th9 cells; on the other hand, it causes resistance against anti-tumor immunity. Despite recent progress, the underlying mechanism reconciling the double-edged effect of TGFβ signaling in Th9-mediated cancer immunotherapy remains elusive. Here, we fi...

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Vydáno v:J Exp Med
Hlavní autoři: Pei, Siyu, Huang, Mingzhu, Huang, Jia, Zhu, Xiaodong, Wang, Hui, Romano, Simona, Deng, Xiuyu, Wang, Yan, Luo, Yixiao, Hao, Shumeng, Xu, Jing, Yu, Tao, Zhu, Qingchen, Yuan, Jia, Shen, Kunwei, Liu, Zhiqiang, Hu, Guohong, Peng, Chao, Luo, Qingquan, Wen, Zhenzhen, Dai, Dongfang, Xiao, Yichuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091105/
https://ncbi.nlm.nih.gov/pubmed/33914044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20202144
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