The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity

T follicular helper (Tfh) cells are crucial for regulating autoimmune inflammation and protective immunity against viral infection. However, the molecular mechanism controlling Tfh cell differentiation is poorly understood. Here, through two mixed bone marrow chimeric experiments, we identified Peli...

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Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Huang, Xinfang, Hao, Shumeng, Liu, Junli, Huang, Yuanyuan, Liu, Manman, Xiao, Chunyuan, Wang, Yan, Pei, Siyu, Yu, Tao, Xu, Jing, Wang, Haikun, Dai, Dongfang, Su, Xiao, Xiao, Yichuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115645/
https://ncbi.nlm.nih.gov/pubmed/33707688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-021-00660-5
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