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Simultaneous Directed Evolution of Coupled Enzymes for Efficient Asymmetric Synthesis of l-Phosphinothricin
The traditional strategy to improve the efficiency of an entire coupled-enzyme system relies on the separate direction of the evolution of enzymes involved in their respective enzymatic reactions. This strategy can lead to enhanced single-enzyme catalytic efficiency but may also lead to a loss of co...
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| Publié dans: | Appl Environ Microbiol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8090864/ https://ncbi.nlm.nih.gov/pubmed/33310717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02563-20 |
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