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Early evolution of efficient enzymes and genome organization

BACKGROUND: Cellular life with complex metabolism probably evolved during the reign of RNA, when it served as both information carrier and enzyme. Jensen proposed that enzymes of primordial cells possessed broad specificities: they were generalist. When and under what conditions could primordial met...

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Detalhes bibliográficos
Main Authors: Szilágyi, András, Kun, Ádám, Szathmáry, Eörs
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534232/
https://ncbi.nlm.nih.gov/pubmed/23114029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-7-38
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