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Local Neutral Networks Help Maintain Inaccurately Replicating Ribozymes

The error threshold of replication limits the selectively maintainable genome size against recurrent deleterious mutations for most fitness landscapes. In the context of RNA replication a distinction between the genotypic and the phenotypic error threshold has been made; where the latter concerns th...

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Autors principals: Szilágyi, András, Kun, Ádám, Szathmáry, Eörs
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192543/
https://ncbi.nlm.nih.gov/pubmed/25299454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109987
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