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PECAM‐1 supports leukocyte diapedesis by tension‐dependent dephosphorylation of VE‐cadherin
Leukocyte extravasation is an essential step during the immune response and requires the destabilization of endothelial junctions. We have shown previously that this process depends in vivo on the dephosphorylation of VE‐cadherin‐Y731. Here, we reveal the underlying mechanism. Leukocyte‐induced stim...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8090850/ https://ncbi.nlm.nih.gov/pubmed/33604918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106113 |
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