Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet

Malnutrition alters leptin signaling, resulting in dysregulation of pituitary somatotropes that may be sex-specific. We reported sex differences in acute fasting responses with reductions in serum leptin in males, but not females (1). Maternal undernutrition can also alter the neonatal leptin surge...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Miles, Tiffany K, Allensworth, Melody Lyn, Moreira, Ana Rita Silva, Odle, Angela Katherine, Haney, Anessa, Lagasse, Alexandra, MacNicol, Angus M, Childs, Gwen V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Neuroendocrinology and Pituitary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090743/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1109
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