SAT-287 Mild Perinatal Undernutrition Results in Underweight Pups and a Premature Neonatal Leptin Surge

Malnutrition causes dysregulated pituitary function, which may in part be due to lowered leptin signals. We showed that loss of somatotrope leptin receptors in mice reduces growth hormone (GH) secretion and promotes metabolic dysfunction in adults. More recently, we showed that adult male mice faste...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Miles, Tiffany K, Allensworth, Melody Lyn, Moreira, Ana Rita Silva, Odle, Angela Katherine, Haney, Anessa, Lagasse, Alexandra, MacNicol, Angus M, Childs, Gwen V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Neuroendocrinology and Pituitary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209610/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1941
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