MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling

Fasting results in a well-established rise in serum growth hormone (GH) in mice and humans. In mice, this coincides with increases in Gh and growth hormone releasing hormone receptor (Ghrhr) mRNA, as well as serum ghrelin. However, fasting also results in a dramatic decline in serum leptin and we ha...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Miles, Tiffany, Silva Moreira, Ana Rita, Allensworth, Melody, Odle, Angela, Haney, Anessa, MacNicol, Angus, Childs, Gwen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2019
Onderwerpen:
Neuroendocrinology and Pituitary
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550701/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-482
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