MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling

Fasting results in a well-established rise in serum growth hormone (GH) in mice and humans. In mice, this coincides with increases in Gh and growth hormone releasing hormone receptor (Ghrhr) mRNA, as well as serum ghrelin. However, fasting also results in a dramatic decline in serum leptin and we ha...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Miles, Tiffany, Silva Moreira, Ana Rita, Allensworth, Melody, Odle, Angela, Haney, Anessa, MacNicol, Angus, Childs, Gwen
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550701/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-482
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