MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling

Fasting results in a well-established rise in serum growth hormone (GH) in mice and humans. In mice, this coincides with increases in Gh and growth hormone releasing hormone receptor (Ghrhr) mRNA, as well as serum ghrelin. However, fasting also results in a dramatic decline in serum leptin and we ha...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Miles, Tiffany, Silva Moreira, Ana Rita, Allensworth, Melody, Odle, Angela, Haney, Anessa, MacNicol, Angus, Childs, Gwen
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
Subjects:
Neuroendocrinology and Pituitary
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550701/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-482
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