Steroid Receptor Co-Activators Regulate Metabolic Kinases to Drive Therapy Resistant ER+ Breast Cancer

Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER+) breast cancer. Disseminated ER+ tumor cells can remain viable but quiescent for years to decades. Contributing factors to metastatic spread include...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Truong, Thu Ha, Benner, Elizabeth A, Hagen, Kyla M, Temiz, Nuri A, Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Pengo, Thomas, Guillen, Katrin P, Welm, Bryan E, Telang, Sucheta, Lange, Carol A, Ostrander, Julie Hanson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Tumor Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089334/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.2111
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