Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models are Promoted by PELP1/AIB1 Complexes

Proline, glutamic acid, and leucine rich protein 1 (PELP1) is overexpressed in approximately 80% of invasive breast tumors. PELP1 dynamically shuttles between the nucleus and cytoplasm, but is primarily nuclear in normal breast tissue. However, altered localization of PELP1 to the cytoplasm is an on...

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Pubblicato in:Mol Cancer Res
Autori principali: Truong, Thu H., Hu, Hsiangyu, Temiz, Nuri A., Hagen, Kyla M., Girard, Brian J., Brady, Nicholas J., Schwertfeger, Kathryn L., Lange, Carol A., Ostrander, Julie H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882512/
https://ncbi.nlm.nih.gov/pubmed/29348189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0598
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