Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates

Progesterone receptors (PRs) are key modifiers of estrogen receptor (ER) target genes and drivers of luminal breast cancer progression. Total PR expression, rather than isoform-specific PR expression, is measured in breast tumors as an indicator of functional ER. We identified phenotypic differences...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Truong, Thu H, Dwyer, Amy R, Diep, Caroline H, Hu, Hsiangyu, Hagen, Kyla M, Lange, Carol A
Format: Artigo
Language:Inglês
Published: Endocrine Society 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349004/
https://ncbi.nlm.nih.gov/pubmed/30597041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00990
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