Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates

Progesterone receptors (PRs) are key modifiers of estrogen receptor (ER) target genes and drivers of luminal breast cancer progression. Total PR expression, rather than isoform-specific PR expression, is measured in breast tumors as an indicator of functional ER. We identified phenotypic differences...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Truong, Thu H, Dwyer, Amy R, Diep, Caroline H, Hu, Hsiangyu, Hagen, Kyla M, Lange, Carol A
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349004/
https://ncbi.nlm.nih.gov/pubmed/30597041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00990
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