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Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates

Progesterone receptors (PRs) are key modifiers of estrogen receptor (ER) target genes and drivers of luminal breast cancer progression. Total PR expression, rather than isoform-specific PR expression, is measured in breast tumors as an indicator of functional ER. We identified phenotypic differences...

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Bibliografiska uppgifter
I publikationen:Endocrinology
Huvudupphovsmän: Truong, Thu H, Dwyer, Amy R, Diep, Caroline H, Hu, Hsiangyu, Hagen, Kyla M, Lange, Carol A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349004/
https://ncbi.nlm.nih.gov/pubmed/30597041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00990
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