Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates

Progesterone receptors (PRs) are key modifiers of estrogen receptor (ER) target genes and drivers of luminal breast cancer progression. Total PR expression, rather than isoform-specific PR expression, is measured in breast tumors as an indicator of functional ER. We identified phenotypic differences...

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Enregistré dans:
Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Truong, Thu H, Dwyer, Amy R, Diep, Caroline H, Hu, Hsiangyu, Hagen, Kyla M, Lange, Carol A
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349004/
https://ncbi.nlm.nih.gov/pubmed/30597041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00990
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