Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates

Progesterone receptors (PRs) are key modifiers of estrogen receptor (ER) target genes and drivers of luminal breast cancer progression. Total PR expression, rather than isoform-specific PR expression, is measured in breast tumors as an indicator of functional ER. We identified phenotypic differences...

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Spremljeno u:
Bibliografski detalji
Izdano u:Endocrinology
Glavni autori: Truong, Thu H, Dwyer, Amy R, Diep, Caroline H, Hu, Hsiangyu, Hagen, Kyla M, Lange, Carol A
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2018
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349004/
https://ncbi.nlm.nih.gov/pubmed/30597041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00990
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